A new video, JAK biology, JAKi in UC (tofacitinib, filgotinib and upadacinitinb) and CD (upadacitinib), safety (PRAC 20 and zoster), positioning, future directions
Thanks for sending research information about the role of RAK inhibitors in treating UC and CD. As I looked up all three drugs: tofacitinib, filgotinib and upadacinitinb, none has been approved for CD. Mr. Lees has mentioned that upadacinitinb is still in phase 2 clinical trial for studying its efficacy in Crohn's patients, as I recall. Does that mean it will be several years before it proves effective or not?
Very interesting video. What is the projected timeline to approval for upadacinitinb for Crohn's in the UK (England)?
Thanks for sending research information about the role of RAK inhibitors in treating UC and CD. As I looked up all three drugs: tofacitinib, filgotinib and upadacinitinb, none has been approved for CD. Mr. Lees has mentioned that upadacinitinb is still in phase 2 clinical trial for studying its efficacy in Crohn's patients, as I recall. Does that mean it will be several years before it proves effective or not?